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SCH-23390 hydrochloride

CAT: 0957-S0476-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-S0476-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
125941-87-9
Synonyms
R- (+) -SCH-23390 hydrochloride, SCH-23390 HCl
Target
Dopamine Receptor
Applications
Neuronal Signaling
Smiles
CN1CCC2=CC (=C (C=C2C (C1) C3=CC=CC=C3) O) Cl.Cl
Molecular Formula
C17H19Cl2NO
Additionnal Information
SCH-23390 hydrochloride (R- (+) -SCH-23390, SCH-23390) is a highly potent and selective dopamine D1-like receptor antagonist with Ki of 0.2 nM and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. SCH-23390 hydrochloride is a potent and high efficacy agonist at h5-HT2C receptors with Ki of 9.3 nM. SCH-23390 hydrochloride directly inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with IC50 of 268 nM.
Storage Conditions
3 years -20°C powder

Chemical Information

SCH-23390 hydrochloride
CAS Number125941-87-9
PubChem CID11957535
IUPAC Name(5R)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrochloride
Molecular FormulaC17H19Cl2NO
Molecular Weight324.2
Topological Polar Surface Area23.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count21
Formal Charge0
Complexity318
SMILES
CN1CCC2=CC(=C(C=C2[C@H](C1)C3=CC=CC=C3)O)Cl.Cl
InChI
InChI=1S/C17H18ClNO.ClH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12;/h2-6,9-10,15,20H,7-8,11H2,1H3;1H/t15-;/m1./s1
InChIKey
OYCAEWMSOPMASE-XFULWGLBSA-N
Chemical Structure
2D Structure
2D structure of SCH-23390 hydrochloride
CAS: 125941-87-9
CID: 11957535
Formula: C17H19Cl2NO
MW: 324.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight324.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass323.0843696
Monoisotopic Mass323.0843696
Topological Polar Surface Area23.5 Ų
Heavy Atom Count21
Formal Charge0
Complexity318
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
HY-19545A-01SCH-23390 (hydrochloride)
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HY-19545B-01(S) -SCH-23390 (hydrochloride)
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