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NPP1-IN-2

CAT: 0804-HY-163448Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163448Size:1 Each
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Description
NPP1-IN-2 (compound 3h) is a potent and selective Ectonucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) inhibitor with IC50 values of 0.55, 3.73 µM for NPP1, NPP3, respectively[1].
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/npp1-in-2.html
Solubility
10 mM in DMSO
Smiles
S=C(N/N=C/C1=CC=C(N2CCOCC2)C=C1)NC3=CC=C4C=CC=CC4=C3
Molecular Formula
C22H22N4OS
Molecular Weight
390.50
References & Citations
[1]Tasleem M, et al. Synthesis, in vitro, and in silico studies of morpholine-based thiosemicarbazones as ectonucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors. Int J Biol Macromol. 2024 Mar 24;266 (Pt 2) :131068.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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