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Piboserod

CAT: 0957-E7701-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E7701-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
152811-62-6
Synonyms
SB-207266
Additionnal Information
Piboserod (SB 207266) is a selective 5-HT (4) receptor antagonist.IC50 value:Target: 5-HT4 antagonistin vitro: Piboserod did not modify the basal contractions but concentration-dependently antagonized the ability of 5-HT to enhance bladder strip contractions to EFS. In presence of 1 and 100 nM of piboserod, the maximal 5-HT-induced potentiations were reduced to 45.0+/-7.9 and 38.7+/-8.7%, respectively .in vivo: Piboserod significantly increased LVEF by 1.7% vs. placebo (CI 0.3, 3.2, P = 0.020), primarily through reduced end-systolic volume from 165 to 158 mL (P = 0.060) . There was a trend for greater increase in LVEF (2.7%, CI -1.1, 6.6, P = 0.15) in a small subset of patients not on chronic beta-blocker therapy. There was no significant eff
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent

Alternative Products

CatalogName
MBS3841159-01Piboserod
DHA27387-01Piboserod hydrochloride
A15542-25Piboserod 25mg
A15542-500Piboserod 500mg
A15542-50Piboserod 50mg
HY-15574APiboserod (hydrochloride)
HY-15574R-01Piboserod (Standard)
A15542-100Piboserod 100mg
A15542-10Piboserod 10mg
A15542-2Piboserod 2mg

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