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CAY10499

CAT: 0957-E5796-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E5796-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
359714-55-9
Synonyms
MAGL-IN-5
Target
Lipase
Applications
Metabolism
Molecular Formula
C18H17N3O5
Additionnal Information
CAY10499 (MAGL-IN-5) is a non-selective lipase inhibitor with IC50 values of 144 nM for human recombinant monoacylglycerol lipase (MAGL), 90 nM for hormone-sensitive lipase (HSL), and 14 nM for fatty acid amide hydrolase (FAAH) . It also inhibits cell growth in MCF-7, MB-231, COV318, OVCAR-3 cancer cell lines.

Chemical Information

Cay10499

CAY10499 is a carbamate ester.

CAS Number359714-55-9
PubChem CID9924775
IUPAC Namebenzyl N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamate
Molecular FormulaC18H17N3O5
Molecular Weight355.3
XLogP3.4
Topological Polar Surface Area89.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count26
Formal Charge0
Complexity547
SMILES
CC1=C(C=CC(=C1)N2C(=O)OC(=N2)OC)NC(=O)OCC3=CC=CC=C3
InChI
InChI=1S/C18H17N3O5/c1-12-10-14(21-18(23)26-17(20-21)24-2)8-9-15(12)19-16(22)25-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3,(H,19,22)
InChIKey
QTENHWTVRQKWRI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Cay10499
CAS: 359714-55-9
CID: 9924775
Formula: C18H17N3O5
MW: 355.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight355.3
XLogP33.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass355.11682065
Monoisotopic Mass355.11682065
Topological Polar Surface Area89.5 Ų
Heavy Atom Count26
Formal Charge0
Complexity547
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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CatalogName
HY-119283-01CAY10499

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