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Guanidine thiocyanate

CAT: 0957-E4830-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E4830-1gSize:1 g
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CAS Number
593-84-0
Target
Others
Applications
Others
Molecular Formula
CH5N3.CHNS
Additionnal Information
Guanidine thiocyanate is a potent inhibitor of nucleases and a powerful denaturant of proteins. It is used for RNA isolation due to its strong chaotropic properties, which effectively denature RNase enzymes in samples, ensuring RNA stability and purity during extraction processes. Nucleic acid extraction buffers containing guanidine thiocyanate effectively deactivate high-titer polioviruses found in potentially infectious materials.

Chemical Information

Guanidine thiocyanate

a powerful chaotropic agent

CAS Number593-84-0
PubChem CID65046
IUPAC Nameguanidine;thiocyanic acid
Molecular FormulaC2H6N4S
Molecular Weight118.16
Topological Polar Surface Area101
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Heavy Atom Count7
Formal Charge0
Complexity57
SMILES
C(#N)S.C(=N)(N)N
InChI
InChI=1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H
InChIKey
ZJYYHGLJYGJLLN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Guanidine thiocyanate
CAS: 593-84-0
CID: 65046
Formula: C2H6N4S
MW: 118.16
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight118.16
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass118.03131738
Monoisotopic Mass118.03131738
Topological Polar Surface Area101 Ų
Heavy Atom Count7
Formal Charge0
Complexity57.6
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
GB0244Guanidine thiocyanate

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