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Aprocitentan

CAT: 0957-E4771-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E4771-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1103522-45-7
Synonyms
ACT-132577
Target
Endothelin Receptor
Applications
GPCR & G Protein
Molecular Formula
C16H14Br2N6O4S
Additionnal Information
Aprocitentan (ACT-132577) is a pharmacologically active metabolite of Macitentan. Aprocitentan is an orally active dual antagonist of ETA/ETB with IC50 values of 3.4 nM and 987 nM, and pA2 values of 6.7 and 5.5, respectively.

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