Aprocitentan D4

• Bioactivity :

  Aprocitentan D4 (ACT-132577 D4) is a deuterium-labeled Aprocitentan. Aprocitentan is a major and pharmacologically active metabolite of Macitentan. Aprocitentan is a dual ETA/ETB antagonist (IC50s: 3.4 nM and 987 nM; pA2s: 6.7 and 5.5) .

• Smiles :

  O=S(N)(NC1=NC=NC(OC([2H])([2H])C([2H])([2H])OC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O

• Molecular Formula :

  C16H10D4Br2N6O4S

• Molecular Weight :

  550.22

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C