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OPB-171775

CAT: 0957-E4695-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-E4695-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2131210-15-4
Target
PDE
Applications
Metabolism
Molecular Formula
C15H18F2N2O3
Additionnal Information
OPB-171775 functions as a molecular glue, promoting the formation of a complex between phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12) . This interaction triggers multiple cellular stresses, ultimately leading to cell death. It also demonstrates significant anticancer activity in patient-derived xenograft (PDX) models of Gastrointestinal stromal tumor (GIST) .

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