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TNG-462

CAT: 0957-E1871-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E1871-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2760483-96-1
Target
PRMT
Applications
Epigenetics
Molecular Formula
C28H36N6O2S
Additionnal Information
TNG-462 is an orally active, potent and selective inhibitor of methylthioadenosine (MTA) -cooperative PRMT5. It exhibits significant antitumor activity, including durable regressions and complete responses, against methylthioadenosine phosphorylase (MTAP) deficiency and/or methylthioadenosine (MTA) accumulation solid tumors.

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