Products for Research Use Only

PBIT

CAT: 0957-E1733-25mgSize: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E1733-25mgSize:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2514-30-9
Target
Histone Demethylase
Applications
Epigenetics
Molecular Formula
C14H11NOS
Additionnal Information
PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. It inhibits JARID1B (KDM5B/PLU1), JARID1Aand JARID1C with an IC50 of 3 μM, 6 μM and 4.9 μM respectively. It is capable of inhibiting the multiplication of breast cancer cell lines expressing high levels of JARIDB1.

Related Products

Popular Products