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RK-701

CAT: 0957-E1607-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E1607-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2648855-18-7
Target
G9a/GLP
Applications
Epigenetics
Molecular Formula
C26H30N4O3
Additionnal Information
RK-701 is a highly selective, potent, and low-toxicity inhibitor of histone methyltransferases G9a and GLP1 with IC50 values of 23-27 nM and 53 nM. RK-701 treatment induces fetal globin expression in human erythroid cells and in mice and plays an essential role in γ-globin induction. RK-701 is used in the research of sickle cell disease.