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Brigimadlin

CAT: 0957-E1491-1mgSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-E1491-1mgSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2095116-40-6
Synonyms
BI 907828
Target
MDM2/MDMX
Applications
Apoptosis
Molecular Formula
C31H25Cl2FN4O3
Additionnal Information
Brigimadlin (BI 907828) is a potent, orally active inhibitor of E3 ubiquitin-protein ligase MDM-2. Brigimadlin inhibits MDM-2's suppression of the tumor suppressor p53. It promotes apoptosis and enhances the transcription of p53 targets such as p21 and PUMA in BT48, BT67, and BT73 cells.

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