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TRUPCR® MYD88 Mutation Detection Kit

CAT: 1219-3B1427Size: 48 ReactionsDry Ice: NoHazardous: No
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CAT#:1219-3B1427Size:48 Reactions
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
• CE-IVD The kit allows highly sensitive and specific diagnosis of MyD88 Mutation in single run. • The kit offers sensitivity to detect as low as 0.5% allele of MyD88 L265P. • All inclusive kit: The Assay includes all the PCR components including PCR Pre-mix / mastermix for optimized results. • Positive control is included in the kit for reliable results
Applications Notes
The TRUPCR® MYD88 Mutation Detection Kit is an in vitro diagnostic test intended for the qualitative detection of L265P mutation in c.794T>C in myeloid differentiation factor 88 (MYD88) gene from tumor tissue DNA (fresh, frozen or formalin fixed paraffin-embedded tissue) /bone marrow or peripheral blood. Results are intended to aid the clinician in classifying patients among Lymphoplasmacyticlymphoma/Waldenstrom Macroglobulinemia (LPL/WM) and nonHodgkin lymphoma and carry out treatment planning. The TRUPCR®MYD88 Mutation Detection Kit is based on allele specific amplification and is achieved by ARMS PCR. The kit is designed to selectively amplify mutant specific sequences in samples that contain a mixture of wild-type and mutated DNA. The TRUPCR®MYD88 Mutation Detection Kit is a single tube kit where the detection is achieved in multiplex reaction using fluorescent probes labeled with FAM (L265P mutation in c.794T>C) and VIC/HEX (reference: a region of MyD88 gene without any known Mpolymorphism/mutation) .

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