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Anti-Olig2

CAT: 1303-OLIG2-0100Size: 500 μLDry Ice: NoHazardous: No
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CAT#:1303-OLIG2-0100Size:500 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OLIG2 (also known as BHLHB1, BHLHE19, PRKCBP2, RACK17) is a basic helix-loop-helix (bHLH) transcription factor essential for oligodendrocyte and motoneuron development in the spinal cord (Ono et al., 2008) . OLIG2 is also known to play a key role in mediating the brains response to cortical injury through post-injury gliosis (Chen Y et al., 2008) and is also highly expressed in malignant glioma where it has been implicated in glioma progression.
Description
Our Anti-Olig2 chicken polyclonal primary antibody from Aves Labs is produced in-house. It detects human, mouse, and rat Olig2, and is affinity-purified IgY. It is great for use in IHC, ICC, WB.
Synonyms
BHLHB1, BHLHE19, PRKCBP2, RACK17
Gene Name
OLIG2
UniProt
Q13516
Host
Chicken
Species Reactivity
Human, Mouse, Rat
Immunogen
N-terminal half of human OLIG2 was used to immunize chickens to avoid cross-reactivity with OLIG3.
Target
Olig2
Clonality
Polyclonal
Isotype
IgY
Type
Primary Antibody
Applications
IHC, ICC, WB
Field of Research
Cell Markers / Glial and Schwann Cell Markers / Neurogenesis and Development / Transcription Regulation
Concentration
0.2 mg/mL
Format
Affinity-Purified IgY
Buffer
Phosphate-buffered saline (10 mM) isotonic (0.9%, w/v) saline (“PBS, " pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
Molecular Weight
35 kDa
Shipping Conditions
Ice packs
Storage Conditions
Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody.
Notes
Eggs from hens hyperimmunized with target were used to prepare an IgY fraction which was then subjected to antigen-specific affinity purification.
IHC Dilution
1:1000
WB Dilution
1:1000
ICC Dilution
1:1000
Quality Control
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used in Western blot on lysate from cells expressing Olig2.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Human
Conjugate
Unconjugated
RRID
AB_2924438

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