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IL-1β (soluble) (human), (recombinant)

CAT: 1106-ALX-522-056-3010Size: 3x 10 μgDry Ice: NoHazardous: No
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CAT#:1106-ALX-522-056-3010Size:3x 10 μg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
IL-1F2, Interleukin-1β
Certification
RUO
UniProt
P01584
Source
Produced in E. coli . Human IL-1β (interleukin-1β) (aa 117-270) is fused to a linker peptide (10 aa) and an N-terminal FLAG ® -tag.
Stability
Stable for at least 6 months after receipt when stored at -20°C.
Concentration
0.1 mg/mL after reconstitution.
Endotoxin
<0.1EU/μg purified protein (LAL test; Associates of CAPE COD Inc.) .
Purity
≥90% (SDS-PAGE)
Reconstitution
Reconstitute with 100μl sterile water.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C
Notes
Historical data has shown that IL-1β activates the NF-κB pathway. FLAG is a registered trademark of Sigma-Aldrich Co.
Specificity
Binds to human IL-1R (interleukin-1 receptor) .
Formulation
Lyophilized. Contains PBS.

UniProtKB · P01584

Interleukin-1 beta

IL1B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01584
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL1B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-1 beta
EC number
—
Processing
Precursor
Secondary accessions
Q53X59, Q53XX2, Q7M4S7, Q7RU01, Q96HE5, Q9UCT6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

CytokineMitogenPyrogen

Cellular component

CytoplasmLysosomeSecreted

Biological process

Inflammatory response

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