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DLL1 (soluble) (human), (recombinant)

CAT: 1106-ALX-201-765-0025Size: 25 µgDry Ice: NoHazardous: No
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CAT#:1106-ALX-201-765-0025Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Delta-like protein 1, Delta1
Certification
RUO
UniProt
O00548
Source
Produced in HEK 293 cells. Recombinant human sDLL-1 contains 522 amino-acid residues.
Stability
The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted sDLL-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C.
Endotoxin
< 0.1 ng per μg of sDLL-1.
Purity
≥95% (SDS-PAGE and HPLC)
Activity
Determined by the dose dependent growth suppression of the human acute monocytic leukemia cell line, THP-1. sDLL-1 inhibits the proliferation in THP-1 cells using a concentration of 3-5 μg/ml.
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water at a concentration of 0.1 – 1mg/ml. Do not vortex. For long term storage, it is recommended to dilute further in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Molecular Weight
~57-60kDa
Shipping Conditions
Blue Ice
Storage Conditions
-20°C
Formulation
Lyophilized from 1X PBS, pH 7.5.
GenBank Number
28514

UniProtKB · O00548

Delta-like protein 1

DLL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00548
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DLL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RAK7, B5M0B3, Q9NU41, Q9UJV2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Autism spectrum disorderEpilepsyIntellectual disability

Cellular component

Cell junctionCell membraneMembrane

Molecular function

Developmental protein

Biological process

DifferentiationNotch signaling pathway

PTM

Disulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

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