Abl1 (human), (recombinant) (His-tag)

CAT: 1106-BML-SE562-0005Size: 5 µgDry Ice: YesHazardous: No

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CAT#:1106-BML-SE562-0005Size:5 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Product Name Alternative

Abelson murine leukemia viral oncogene homolog 1

Certification

RUO

UniProt

P00519

Source

Produced in insect cells. Produced in a baculovirus expression system.

Sequence

Human recombinant Abl1 (aa 27-1130) with N-terminal histidine tag.

Purity

≥70% (SDS-PAGE)

Molecular Weight

~135kDa

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Formulation

Liquid. In 50mM sodium phosphate, pH 7.0, containing 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.

Applications Notes

Useful tool to study enzyme regulation and kinetics, phosphorylate target substrates, screen for inhibitors.

UniProtKB · P00519

Tyrosine-protein kinase ABL1

ABL1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P00519
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ABL1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 2.7.10.2
Processing: —
Secondary accessions: A3KFJ3, Q13869, Q13870, Q16133, Q17R61, Q45F09

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationLipoproteinMyristatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Biological process

ApoptosisAutophagyCell adhesionDNA damageDNA repairEndocytosis

Ligand

ATP-bindingMagnesiumManganeseMetal-bindingNucleotide-binding

Cellular component

CytoplasmCytoskeletonMembraneMitochondrionNucleus

Disease

Disease variantProto-oncogene

Molecular function

DNA-bindingKinaseTransferaseTyrosine-protein kinase

Domain

SH2 domainSH3 domain

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Alternative Products

Catalog	Name
MBS566701-01	Abl1 (human), (recombinant) (His-tag)
Z500001	Recombinant Human ABL1 (N-His tag)
MBS4160413-01	Recombinant Mouse ABL1 (N-His tag)
PDEH100797-01	Recombinant Human ABL1/c-Abl protein (His tag)
590641-01	ABL1/c-Abl, Recombinant, Human, His-Tag discontinued
PDEC100003-01	Recombinant Cynomolgus macaques ABL1 protein (His tag)
590640-01	ABL1, Recombinant, Cynomolgus Macaques, His-Tag discontinued
MBS517846-01	Recombinant Human c-Abl/ABL1 Protein (K290R, His Tag)
PDEM100288-01	Recombinant Mouse ABL1/c-Abl protein (His tag)
590642-01	ABL1/c-Abl, Recombinant, Mouse, His-Tag discontinued