#NAME?

CAT: 0063-44241417Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0063-44241417Size:100 mg

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CAS Number

485-49-4

Chemical Information

Bicuculline

Bicuculline is a benzylisoquinoline alkaloid that is 6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinoline which is substituted at the 5-pro-S position by a (6R)-8-oxo-6,8-dihydrofuro[3,4-e][1,3]benzodioxol-6-yl group. A light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. It has a role as a GABAA receptor antagonist, an agrochemical, a central nervous system stimulant, a GABA-gated chloride channel antagonist and a neurotoxin. It is a benzylisoquinoline alkaloid, an isoquinoline alkaloid and a member of isoquinolines.

CAS Number	485-49-4
PubChem CID	10237
IUPAC Name	(6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one
Molecular Formula	C20H17NO6
Molecular Weight	367.4
XLogP	2.6
Topological Polar Surface Area	66.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	1
Heavy Atom Count	27
Formal Charge	0
Complexity	615

SMILES

CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3

InChI

InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1

InChIKey

IYGYMKDQCDOMRE-ZWKOTPCHSA-N

Chemical Structure

2D Structure

CAS: 485-49-4

CID: 10237

Formula: C20H17NO6

MW: 367.4

Interactive 3D Structure

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Computed Properties

Property	Value
Molecular Weight	367.4
XLogP3	2.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	1
Exact Mass	367.10558726
Monoisotopic Mass	367.10558726
Topological Polar Surface Area	66.5 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	615
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
GTR18315492	#NAME?
HY-18729	L-NAME
A7088-100	L-NAME hydrochloride
ALX-105-003-G005	L-NAME . hydrochloride
T36719-01	D-NAME (hydrochloride)
ProductCode	Antibody product name
S2877-1g	L-NAME HCl

#NAME?

Chemical Information

Alternative Products

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