D-NAME (hydrochloride)

CAT: 0931-T36719-01Size: 250 mgDry Ice: NoHazardous: No

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CAT#:0931-T36719-01Size:250 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

50912-92-0

Target

Others, NO Synthase

Related Pathways

Immunology/Inflammation, Others

Bioactivity

N (G) -Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N (G) -nitro-L-arginine methyl ester . D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Later studies showed that D-NAME (40 mg/kg/day in rats) can have similar but less pronounced effects as L-NAME (40 mg/kg/day in rats) in the cardiovascular system, particularly at long-term timepoints. D-NAME (3-10 µg/mouse) had no effect on nociception in mice assessed using the tail flick test.

Smiles

COC(=O)[C@H](N)CCCNC(=N)N[N+]([O-])=O

Molecular Formula

C7H16ClN5O4

Molecular Weight

269.69

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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D-NAME (hydrochloride)

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