Products for Research Use Only
RegisterLogin

Olmutinib (BI 1482694)

CAT: 1568-C18152Size: 100 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:1568-C18152Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1353550-13-6
Synonyms
HM61713
SKU
C18152-100mg
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) C2=CC=C (C=C2) NC3=NC4=C (C (=N3) OC5=CC=CC (=C5) NC (=O) C=C) SC=C4
Molecular Formula
C26H26N6O2S
Additionnal Information
Olmutinib (BI 1482694) is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor (TKI) . Also a potent inhibitor of Bruton's tyrosine kinase.
Storage Conditions
2 years -80 in solvent

Chemical Information

Olmutinib

Olmutinib is an orally active epidermal growth factor receptor inhibitor used in the treatment of T790M mutation positive non-small cell lung cancer. It is available under the brand name Olita made by Hanmi Pharmaceuticals. Olmutinib was developed by Hanmi Pharmaceuticals and Boehringer Ingelheim. Olmutinib recieved breakthrough therapy designation in the United States in December 2015 and was approved for use in Korea in May 2016.

CAS Number1353550-13-6
PubChem CID54758501
IUPAC NameN-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Molecular FormulaC26H26N6O2S
Molecular Weight486.6
XLogP4.7
Topological Polar Surface Area111
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Heavy Atom Count35
Formal Charge0
Complexity712
SMILES
CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC4=C(C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)SC=C4
InChI
InChI=1S/C26H26N6O2S/c1-3-23(33)27-19-5-4-6-21(17-19)34-25-24-22(11-16-35-24)29-26(30-25)28-18-7-9-20(10-8-18)32-14-12-31(2)13-15-32/h3-11,16-17H,1,12-15H2,2H3,(H,27,33)(H,28,29,30)
InChIKey
FDMQDKQUTRLUBU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Olmutinib
CAS: 1353550-13-6
CID: 54758501
Formula: C26H26N6O2S
MW: 486.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight486.6
XLogP34.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass486.18379527
Monoisotopic Mass486.18379527
Topological Polar Surface Area111 Ų
Heavy Atom Count35
Formal Charge0
Complexity712
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
C01739-01BI-2493
C03747(±) -BI-D
C07479-10mM/1mLBI-1347
C07526-50mgBI 2536
C15896-25mgBI 01383298
C16116-01BI 2536
C17096BI-D1870
C11993-01BI-4464
C12991-01BI-847325
C13627-01BI-3812

Alternative Products

CatalogName
S8294-25mgOlmutinib (BI 1482694)
B7813-5.1Olmutinib (HM61713, BI 1482694)
MBS3601438-01Olmutinib
GTR19163767-01Olmutinib (b)
MBS5812670Olmutinib hydrochloride
MBS3841294-01Olmutinib (HM71224)
HY-19730AOlmutinib (hydrochloride)

Popular Products