LY2109761

CAT: 1568-C17016Size: 10 mgDry Ice: YesHazardous: No
CAT#:1568-C17016Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
700874-71-1
SKU
C17016-10mg
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
C1CC2=C (C (=NN2C1) C3=CC=CC=N3) C4=C5C=CC (=CC5=NC=C4) OCCN6CCOCC6
Molecular Formula
C26H27N5O2
Additionnal Information
LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2. LY2109761 blocks autophagy and induces apoptosis.
Storage Conditions
2 years -80 in solvent

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