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LY2109761

CAT: 0957-S2704-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2704-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2. LY2109761 blocks autophagy and induces apoptosis.
CAS Number
700874-71-1
Target
TGF-beta/Smad
Activity
TGF-beta/Smad
Molecular Formula
C26H27N5O2
Storage Conditions
2 years -80 in solvent