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TG101209

CAT: 1568-C17007-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:1568-C17007-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
936091-14-4
SKU
C17007-10mg
Target
C-RET
Applications
Protein Tyrosine Kinase
Smiles
CC1=CN=C (N=C1NC2=CC (=CC=C2) S (=O) (=O) NC (C) (C) C) NC3=CC=C (C=C3) N4CCN (CC4) C
Molecular Formula
C26H35N7O2S
Additionnal Information
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET (c-RET) with IC50 of 25 nM and 17 nM in cell-free assays, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations.
Storage Conditions
2 years -80 in solvent

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A11180-2TG101209 2mg

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