Mitoxantrone 2HCl

• CAS Number :

  70476-82-3

• Synonyms :

  NSC-301739 2HCl, Mitozantrone 2HCl

• SKU :

  C16871-100mg

• Target :

  Topoisomerase

• Applications :

  DNA Damage/DNA Repair

• Smiles :

  C1=CC (=C2C (=C1NCCNCCO) C (=O) C3=C (C=CC (=C3C2=O) O) O) NCCNCCO.Cl.Cl

• Molecular Formula :

  C22H29ClN4O6.2HCl

• Additionnal Information :

  Mitoxantrone 2HCl is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.

• Storage Conditions :

  2 years -80 in solvent