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Mitoxantrone 2HCl

CAT: 0957-S2485-01Size: 50 mgDry Ice: YesHazardous: No
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CAT#:0957-S2485-01Size:50 mg
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Description
Mitoxantrone 2HCl is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.
CAS Number
70476-82-3
Synonyms
NSC-301739 2HCl, Mitozantrone 2HCl
Target
Topoisomerase
Activity
DNA Damage/DNA Repair
Molecular Formula
C22H29ClN4O6.2HCl
Storage Conditions
2 years -80 in solvent

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