PF-04995274

CAT: 1568-C15975Size: 25 mgDry Ice: NoHazardous: No
CAT#:1568-C15975Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1331782-27-4
Synonyms
PF-4995274
SKU
C15975-25mg
Target
5-HT Receptor
Applications
Neuronal Signaling
Smiles
C1CN (CCC1COC2=NOC3=C2C (=CC=C3) OC4CCOC4) CC5 (CCOCC5) O
Molecular Formula
C23H32N2O6
Additionnal Information
PF-04995274 (PF-4995274) is a potent, high-affinity, orally active and partial agonist of serotonin 4 receptor (5-HT4R) with EC50 of 0.47 nM, 0.36 nM, 0.37 nM and 0.26 nM for human 5-HT4A/4B/4D/4E, respectively. As for rat 5-HT4S/4L/4E, the EC50 is 0.59 nM, 0.65 nM and 0.62 nM, respectively. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease.
Storage Conditions
3 years -20°C powder

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