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Puromycin aminonucleoside

CAT: 1568-C14375-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C14375-01Size:5 mg
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CAS Number
58-60-6
Synonyms
NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN
SKU
C14375-5mg
Target
DPP
Applications
Metabolism
Molecular Formula
C12H18N6O3
Additionnal Information
Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN), the aminonucleoside portion of the antibiotic puromycin, is a reversible inhibitor of dipeptidyl-peptidase II and cytosol alanyl aminopeptidase that induces apoptosis in mesangial cells (MCs) accompanied by declined cell viability and enhanced inflammatory response.Puromycin aminonucleoside can be used to induce animal models of Kidney Disease.
Storage Conditions
3 years -20°C powder

Chemical Information

Aminonucleoside

3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine is puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring. It is a member of adenosines and a 3'-deoxyribonucleoside.

CAS Number58-60-6
PubChem CID6020
IUPAC Name(2R,3R,4S,5S)-4-amino-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolan-3-ol
Molecular FormulaC12H18N6O3
Molecular Weight294.31
XLogP-0.5
Topological Polar Surface Area123
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Heavy Atom Count21
Formal Charge0
Complexity373
SMILES
CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)N)O
InChI
InChI=1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7-,9-,12-/m1/s1
InChIKey
RYSMHWILUNYBFW-GRIPGOBMSA-N
Chemical Structure
2D Structure
2D structure of Aminonucleoside
CAS: 58-60-6
CID: 6020
Formula: C12H18N6O3
MW: 294.31
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight294.31
XLogP3-0.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass294.14403846
Monoisotopic Mass294.14403846
Topological Polar Surface Area123 Ų
Heavy Atom Count21
Formal Charge0
Complexity373
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
P041-500MGPuromycin Aminonucleoside

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