BAY-985

• CAS Number :

  2409479-29-2

• SKU :

  C13797-5mg

• Target :

  TBK1

• Applications :

  Immunology & Inflammation

• Smiles :

  CC (C1=CC (=NC=C1) NC2=NC3=C (N2) C=C (C=C3) C4=CC (=NC=N4) N (C) C) N5CCN (CC5) C (=O) CC (F) (F) F

• Molecular Formula :

  C27H30F3N9O

• Additionnal Information :

  BAY-985 is a potent and highly selective TBK1/IKKε inhibitor. BAY-985 shows high potency toward TBK1 (IC50 = 2 nM, low ATP assay; 30 nM, high ATP assay) and IKKε (IC50 = 2 nM), as well as high potency in the mechanistic pIRF3 assay (IC50 = 74 nM), and an antiproliferative effect on SK-MEL-2 cells (IC50 = 900 nM) .

• Storage Conditions :

  3 years -20°C powder