JHU-083

• CAS Number :

  1998725-11-3

• Synonyms :

  Ethyl 2- (2-Amino-4-methylpentanamido) -DON

• SKU :

  C13755-2mg

• Target :

  Glutaminase

• Applications :

  Proteases

• Smiles :

  CCOC (=O) C (CCC (=O) C=[N+]=[N-]) NC (=O) C (CC (C) C) N

• Molecular Formula :

  C14H24N4O4

• Additionnal Information :

  JHU-083 (Ethyl 2- (2-Amino-4-methylpentanamido) -DON) is a novel prodrug of DON.JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress.Solutions are unstable and should be fresh-prepared.