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FG-2216

CAT: 1568-C13099-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:1568-C13099-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
223387-75-5
SKU
C13099-5mg
Target
HIF
Applications
Angiogenesis
Smiles
C1=CC=C2C (=C1) C (=C (N=C2Cl) C (=O) NCC (=O) O) O
Molecular Formula
C12H9ClN2O4
Additionnal Information
FG-2216 is a potent, and orally active HIF prolyl 4-hydroxylase inhibitor with IC50 of 3.9 μM for PHD2. Phase 2.
Storage Conditions
2 years -80 in solvent

Chemical Information

FG-2216

A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.

CAS Number223387-75-5
PubChem CID6914666
IUPAC Name2-[(1-chloro-4-hydroxyisoquinoline-3-carbonyl)amino]acetic acid
Molecular FormulaC12H9ClN2O4
Molecular Weight280.66
XLogP2.5
Topological Polar Surface Area99.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count19
Formal Charge0
Complexity366
SMILES
C1=CC=C2C(=C1)C(=C(N=C2Cl)C(=O)NCC(=O)O)O
InChI
InChI=1S/C12H9ClN2O4/c13-11-7-4-2-1-3-6(7)10(18)9(15-11)12(19)14-5-8(16)17/h1-4,18H,5H2,(H,14,19)(H,16,17)
InChIKey
OUQVKRKGTAUJQA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of FG-2216
CAS: 223387-75-5
CID: 6914666
Formula: C12H9ClN2O4
MW: 280.66
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight280.66
XLogP32.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass280.0250845
Monoisotopic Mass280.0250845
Topological Polar Surface Area99.5 Ų
Heavy Atom Count19
Formal Charge0
Complexity366
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
M13580-01FG-2216
TRC-F329000-25MGFG 2216
HY-15641R-01FG-2216 (Standard)
B2739-25IOX3 (FG-2216)
A15530-5FG-2216 5mg
A15530-50FG-2216 50mg
A15530-200FG-2216 200mg
A15530-100FG-2216 100mg
A15530-10FG-2216 10mg
A15530-25FG-2216 25mg

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