Niraparib tosylate

• CAS Number :

  1038915-73-9

• Synonyms :

  MK 4827 tosylate

• SKU :

  C12825-5mg

• Target :

  PARP

• Applications :

  DNA Damage/DNA Repair

• Smiles :

  CC1=CC=C (C=C1) S (=O) (=O) O.C1CC (CNC1) C2=CC=C (C=C2) N3C=C4C=CC=C (C4=N3) C (=O) N

• Molecular Formula :

  C19H20N4O.C7H8O3S

• Additionnal Information :

  Niraparib tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.

• Storage Conditions :

  2 years -80 in solvent