Niraparib hydrochloride

CAT: 1568-C03419-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:1568-C03419-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1038915-64-8
Synonyms
MK-4827 hydrochloride
SKU
C03419-5mg
Target
PARP
Applications
DNA Damage/DNA Repair
Additionnal Information
Niraparib hydrochloride (MK-4827 hydrochloride) is a potent poly (ADP-ribose) polymerase (PARP) inhibitor with IC50s of 3.8 and 2.1 nM against both the PARP-1 and PARP-2 enzymes, respectively.It inhibits the repair of radiation-induced DNA double-strand breaks, activates apoptosis, and exhibits anti-tumor activity.

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