Products for Research Use Only
RegisterLogin

RG2833 (RGFP109)

CAT: 1568-C12577-01Size: 10 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:1568-C12577-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1215493-56-3
SKU
C12577-10mg
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CC1=CC=C (C=C1) C (=O) NCCCCCC (=O) NC2=CC=CC=C2N
Molecular Formula
C20H25N3O2
Additionnal Information
RG2833 (RGFP109) is a brain-penetrant HDAC inhibitor with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3 in cell-free assays, respectively.
Storage Conditions
2 years -80 in solvent

Chemical Information

RG-2833

RG-2833 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 4-methylbenzoic acid with the primary amino group of 6-amino-N-(2-aminophenyl)hexanamide. It is a HDAC1 and HDAC3 inhibitor with established brain penetration. It has a role as an antineoplastic agent, an EC 3.5.1.98 (histone deacetylase) inhibitor and a nootropic agent. It is an anilide, a secondary carboxamide, a member of benzamides, a member of toluenes and a substituted aniline. It is functionally related to a 6-aminohexanoic acid.

CAS Number1215493-56-3
PubChem CID56654642
IUPAC NameN-[6-(2-aminoanilino)-6-oxohexyl]-4-methylbenzamide
Molecular FormulaC20H25N3O2
Molecular Weight339.4
XLogP2.8
Topological Polar Surface Area84.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count8
Heavy Atom Count25
Formal Charge0
Complexity419
SMILES
CC1=CC=C(C=C1)C(=O)NCCCCCC(=O)NC2=CC=CC=C2N
InChI
InChI=1S/C20H25N3O2/c1-15-10-12-16(13-11-15)20(25)22-14-6-2-3-9-19(24)23-18-8-5-4-7-17(18)21/h4-5,7-8,10-13H,2-3,6,9,14,21H2,1H3,(H,22,25)(H,23,24)
InChIKey
VOPDXHFYDJAYNS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of RG-2833
CAS: 1215493-56-3
CID: 56654642
Formula: C20H25N3O2
MW: 339.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight339.4
XLogP32.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count8
Exact Mass339.19467705
Monoisotopic Mass339.19467705
Topological Polar Surface Area84.2 Ų
Heavy Atom Count25
Formal Charge0
Complexity419
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
S7292-01RG2833 (RGFP109)
A13139-500RG2833 (RGFP109) 500mg
A13139-5RG2833 (RGFP109) 5mg
A13139-100RG2833 (RGFP109) 100mg
A13139-200RG2833 (RGFP109) 200mg
bs-60225C-01RG2833 (RGFP109) --- Brain-penetrant HDAC Inhibitor
A3761-5.1RG2833
A13139-50RG2833 50mg
A13139-25RG2833 25mg
A13139-10RG2833 10mg

Popular Products