(+) -JQ1

CAT: 1568-C12450-01Size: 10 mgDry Ice: YesHazardous: No
CAT#:1568-C12450-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1268524-70-4
SKU
C12450-10mg
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) OC (C) (C) C) C4=CC=C (C=C4) Cl) C
Molecular Formula
C23H25ClN4O2S
Additionnal Information
(+) -JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4 (1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+) -JQ1 suppresses cell proliferation via inducing autophagy. (+) -JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
Storage Conditions
2 years -80 in solvent

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