Binimetinib (MEK162)

CAT: 1568-C12377-01Size: 10 mgDry Ice: YesHazardous: No
CAT#:1568-C12377-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
606143-89-9
Synonyms
ARRY-162, ARRY-438162
SKU
C12377-10mg
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
CN1C=NC2=C1C=C (C (=C2F) NC3=C (C=C (C=C3) Br) F) C (=O) NOCCO
Molecular Formula
C17H15BrF2N4O3
Additionnal Information
Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Binimetinib induces G1 cell cycle arrest and apoptosis in human NSCLC cell lines and induces autophagy. Phase 3.
Storage Conditions
2 years -80 in solvent

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