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Gefapixant

CAT: 1568-C12105-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C12105-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1015787-98-0
Synonyms
AF-219, MK-7264, R1646, RG-1646, RO 4926219
SKU
C12105-5mg
Target
P2 Receptor
Applications
Neuronal Signaling
Smiles
CC (C) C1=CC (=C (C=C1OC2=CN=C (N=C2N) N) S (=O) (=O) N) OC
Molecular Formula
C14H19N5O4S
Additionnal Information
Gefapixant (AF-219, MK-7264, R1646, RG-1646, RO 4926219) is an orally active small molecule antagonist of human P2X3 receptor with IC50 of about 30 nM, 100–250 nM for recombinant hP2X3 homotrimers and hP2X2/3 heterotrimeric receptors, respectively. Gefapixant has shown promise for the treatment of refractory and unexplained chronic cough.
Storage Conditions
3 years -20°C powder

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