Pemetrexed

• CAS Number :

  137281-23-3

• Synonyms :

  LY231514

• SKU :

  C11508-25mg

• Target :

  Thymidylate Synthase

• Applications :

  Apoptosis

• Smiles :

  NC1=NC (=O) C2=C ([NH]C=C2CCC3=CC=C (C=C3) C (=O) NC (CCC (O) =O) C (O) =O) N1

• Molecular Formula :

  C20H21N5O6

• Additionnal Information :

  Pemetrexed (LY231514) is a novel antifolate and antimetabolite for thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT) with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis.

• Storage Conditions :

  3 years -20°C powder