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Terfenadine

CAT: 1568-C10106Size: 25 mgDry Ice: YesHazardous: No
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CAT#:1568-C10106Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
50679-08-8
SKU
C10106-25mg
Target
Potassium Channel
Applications
Transmembrane Transporters
Smiles
CC (C) (C) C1=CC=C (C=C1) C (CCCN2CCC (CC2) C (C3=CC=CC=C3) (C4=CC=CC=C4) O) O
Molecular Formula
C32H41NO2
Additionnal Information
Terfenadine is an antihistamine, generally completely metabolizes to the active form fexofenadine in the liver by the enzyme cytochrome P450 CYP3A4 isoform. Terfenadine ((±) -Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
Storage Conditions
2 years -80 in solvent

Alternative Products

CatalogName
MBS6106930-01Terfenadine

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