Purmorphamine

• CAS Number :

  483367-10-8

• Synonyms :

  Shh Signaling Antagonist VI

• SKU :

  C09061-5mg

• Target :

  Autophagy

• Applications :

  Autophagy

• Smiles :

  C1CCC (CC1) N2C=NC3=C (N=C (N=C32) OC4=CC=CC5=CC=CC=C54) NC6=CC=C (C=C6) N7CCOCC7

• Molecular Formula :

  C31H32N6O2

• Additionnal Information :

  Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM. Purmorphamine can reduce both basal and induced autophagy.

• Storage Conditions :

  2 years -80 in solvent