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Tofacitinib

CAT: 1568-C08859-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:1568-C08859-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
477600-75-2
Synonyms
CP-690550, Tasocitinib
SKU
C08859-5mg
Target
JAK
Applications
Angiogenesis
Smiles
CC1CCN (CC1N (C) C2=NC=NC3=C2C=CN3) C (=O) CC#N
Molecular Formula
C16H20N6O
Additionnal Information
Tofacitinib is a novel inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, 20- to 100-fold less potent against JAK2 and JAK1. Tofacitinib inhibits the expression of antiapoptotic BCL-A1 and BCL-XL in human plasmacytoid dendritic cells (PDC) and induced PDC apoptosis.
Storage Conditions
2 years -80 in solvent

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