PF-5274857

CAT: 1568-C08849Size: 5 mgDry Ice: YesHazardous: No
CAT#:1568-C08849Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1373615-35-0
SKU
C08849-5mg
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
CC1=CC (=C (N=C1) C2=CC (=NC=C2Cl) N3CCN (CC3) C (=O) CCS (=O) (=O) C) C
Molecular Formula
C20H25ClN4O3S
Additionnal Information
PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier.
Storage Conditions
2 years -80 in solvent

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T5465-01PF-5274857
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