Rabusertib (LY2603618)

CAT: 1568-C08731-01Size: 5 mgDry Ice: YesHazardous: No
CAT#:1568-C08731-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
911222-45-2
Synonyms
IC-83
SKU
C08731-5mg
Target
Chk
Applications
Cell Cycle
Smiles
CC1=CC (=C (C=C1Br) NC (=O) NC2=NC=C (N=C2) C) OCC3CNCCO3
Molecular Formula
C18H22BrN5O3
Additionnal Information
Rabusertib (LY2603618, IC-83) is a highly selective Chk1 inhibitor with potential anti-tumor activity in a cell-free assay. IC50=7 nM, showing approximately 100-fold more potent against Chk1 than against any of the other protein kinases evaluated. Rabusertib (LY2603618) induces cell cycle arrest, DNA damage response and autophagy in cancer cells. Rabusertib (LY2603618) induces bak-dependent apoptosis in AML cell lines.
Storage Conditions
2 years -80 in solvent

Related Products

CatalogName
C11847-01Prexasertib (LY2606368)
C12505-01Prexasertib HCl (LY2606368)

Alternative Products

CatalogName
201794Rabusertib (LY2603618)
A11036-10Rabusertib (LY2603618, IC-83) 10mg
A11036-50Rabusertib (LY2603618, IC-83) 50mg
A11036-25Rabusertib (LY2603618, IC-83) 25mg
A11036-100Rabusertib (LY2603618, IC-83) 100mg
A11036-5Rabusertib (LY2603618, IC-83) 5mg
A11036-200Rabusertib (LY2603618, IC-83) 200mg
A11036-10mM-DRabusertib (LY2603618, IC-83) (IC-83) 10mM * 1mL in DMSO
BUP15451-01Rabusertib
M16540-01LY2603618

Popular Products