AMG-47a

• CAS Number :

  882663-88-9

• SKU :

  C08361-5mg

• Target :

  Src

• Applications :

  Protein Tyrosine Kinase

• Smiles :

  CC1=C (C=C (C=C1) C (=O) NC2=CC=CC (=C2) C (F) (F) F) C3=CC4=CN=C (N=C4C=C3) NCCN5CCOCC5

• Molecular Formula :

  C29H28F3N5O2

• Additionnal Information :

  AMG-47a is a potent, nonselective inhibitor of Lck kinase with IC50 of 3.4 uM and it also inhibits T cell proliferation. AMG-47a exhibit anti-inflammatory activity (ED50) of 11 mg/kg in the anti-CD3-induced production of interleukin-2 (IL-2) in mice.

• Storage Conditions :

  3 years -20°C powder