AMG-458

• CAS Number :

  913376-83-7

• SKU :

  C08824-5mg

• Target :

  C-Met

• Applications :

  Protein Tyrosine Kinase

• Smiles :

  CC1=C (C (=O) N (N1CC (C) (C) O) C2=CC=CC=C2) C (=O) NC3=NC=C (C=C3) OC4=C5C=CC (=CC5=NC=C4) OC

• Molecular Formula :

  C30H29N5O5

• Additionnal Information :

  AMG 458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.

• Storage Conditions :

  2 years -80 in solvent