AMG-208

CAT: 1568-C07704Size: 10 mgDry Ice: YesHazardous: No

CAT#:1568-C07704Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1002304-34-8

SKU

C07704-10mg

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

COC1=CC2=NC=CC (=C2C=C1) OCC3=NN=C4N3N=C (C=C4) C5=CC=CC=C5

Molecular Formula

C22H17N5O2

Additionnal Information

AMG 208 is a highly selective dual c-Met and RON inhibitor with IC50 of 9 nM for c-Met.

Storage Conditions

2 years -80 in solvent

1002304-34-8

PubChem

cas	1002304-34-8
modify	2026-05-17
description	AMG-208 is a member of the class of quinolines that is 7-methoxyquinoline substituted at position 4 by a (6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy group. AMG exhibits antitumour activity, particularly in prostate cancer. It has a role as an antineoplastic agent and a c-Met tyrosine kinase inhibitor. It is a member of quinolines, an aromatic ether and a triazolopyridazine.
synonyms	AMG-2081002304-34-8AMG 208AMG208 7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Y2SR66P7VM 7-methoxy-4-[(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline Quinoline, 7-methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]- AMG 208 [WHO-DD]+ 15 more
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