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Cisplatin

CAT: 1568-C07576-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:1568-C07576-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
15663-27-1
Synonyms
NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP
SKU
C07576-10g
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
[NH2-].[NH2-].Cl[Pt+2]Cl
Molecular Formula
Cl2H6N2Pt
Additionnal Information
Cisplatin is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts in tumor cells. Cisplatin activates ferroptosis and induces autophagy.Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
Storage Conditions
2 years -80 in solvent

Chemical Information

Cisplatin

Platinol appears as an anticancer drug. Orange-yellow to deep yellow solid or powder. (NTP, 1992)

CAS Number15663-27-1
PubChem CID5460033
IUPAC Nameazane;dichloroplatinum
Molecular FormulaCl2H6N2Pt
Molecular Weight300.05
Topological Polar Surface Area2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Heavy Atom Count5
Formal Charge0
Complexity7
SMILES
N.N.Cl[Pt]Cl
InChI
InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
InChIKey
LXZZYRPGZAFOLE-UHFFFAOYSA-L
Chemical Structure
2D Structure
2D structure of Cisplatin
CAS: 15663-27-1
CID: 5460033
Formula: Cl2H6N2Pt
MW: 300.05
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight300.05
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass298.955598
Monoisotopic Mass298.955598
Topological Polar Surface Area2 Ų
Heavy Atom Count5
Formal Charge0
Complexity7.6
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes

Alternative Products

CatalogName
A8321-500Cisplatin

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