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TRAM-34

CAT: 1568-C07570-02Size: 25 mgDry Ice: YesHazardous: No
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CAT#:1568-C07570-02Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
289905-88-0
Synonyms
Triarylmethane-34
SKU
C07570-5mg
Target
Potassium Channel
Applications
Transmembrane Transporters
Smiles
C1=CC=C (C=C1) C (C2=CC=CC=C2) (C3=CC=CC=C3Cl) N4C=CC=N4
Molecular Formula
C22H17ClN2
Additionnal Information
TRAM-34 (Triarylmethane-34) is a selective and potent inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1) with Kd of 20 nM, 200- to 1500-fold selective over other ion channels, and does not block cytochrome P450.
Storage Conditions
2 years -80 in solvent

Chemical Information

Tram-34

TRAM-34 is an organochlorine compound.

CAS Number289905-88-0
PubChem CID656734
IUPAC Name1-[(2-chlorophenyl)-diphenylmethyl]pyrazole
Molecular FormulaC22H17ClN2
Molecular Weight344.8
XLogP5.6
Topological Polar Surface Area17.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count4
Heavy Atom Count25
Formal Charge0
Complexity396
SMILES
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CC=N4
InChI
InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H
InChIKey
KBFUQFVFYYBHBT-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tram-34
CAS: 289905-88-0
CID: 656734
Formula: C22H17ClN2
MW: 344.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight344.8
XLogP35.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count4
Exact Mass344.1080262
Monoisotopic Mass344.1080262
Topological Polar Surface Area17.8 Ų
Heavy Atom Count25
Formal Charge0
Complexity396
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS130644-01TRAM-34
2946/50TRAM 34
A12783-500TRAM-34 500mg
A12783-10TRAM-34 10mg
A12783-5TRAM-34 5mg
A12783-200TRAM-34 200mg

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