Filipin complex

CAT: 1568-C04811Size: 5 mgDry Ice: NoHazardous: No
CAT#:1568-C04811Size:5 mg
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CAS Number
11078-21-0
SKU
C04811-5mg
Target
Antiviral
Applications
Microbiology
Additionnal Information
Filipin complex is a potent polyene macrolide antifungal antibiotic that integrates into membranes, sequestering cholesterol into complexes. Its treatment reduces PRRSV genome copies by 61% and lowers the PRRSV titer. It also acts as a fluorescent histochemical stain prone to autooxidation, commonly used in diagnosing Niemann-Pick Disease Type C (NP-C), a neurodegenerative lysosomal storage disorder. Researchers also employ it to study unesterified cholesterol distribution in cell and animal models of neurodegenerative diseases like NP-C and Sanfilippo syndrome (MPS IIIA) .

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