AF12198

CAT: 1568-C04444Size: 1 mgDry Ice: YesHazardous: No

CAT#:1568-C04444Size:1 mg

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PRICE

AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

185413-30-3

SKU

C04444-1mg

Additionnal Information

AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 μM) or the murine type I receptor (IC50>200 μM) . AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory activities and blocks responses to IL-1 in vivo.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

Alternative Products

Catalog	Name
HY-P1110-01	AF12198
CRB1001289-01	AF12198 - (Immunology - Antigens/Epitotes/Pools/Librairies)

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