W-13 (hydrochloride)

W-13 (hydrochloride)

• CAS Number: 88519-57-7
• UNSPSC Description: W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth[1].
• Target Antigen: CaMK
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/w-13-hydrochloride.html
• Purity: 99.86
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O=S(C1=CC=C2C(Cl)=CC=CC2=C1)(NCCCCN)=O.[H]Cl
• Molecular Weight: 349.28
• References & Citations: [1]Tallant EA, et, al. Calmodulin antagonists elevate the levels of 32P-labeled polyphosphoinositides in human platelets. Biochem Biophys Res Commun. 1985 Aug 30;131(1):370-7.|[2]Strobl JS, et, al. Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13. J Pharmacol Exp Ther. 1992 Oct;263(1):186-93.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported